About 7 results found for searched term "HSP70-IN-1" (0.119 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9273 | HSP70-IN-1 | HSP |
| HSP70-IN-1 is a heat shock protein (HSP) inhibitor with an IC50 of 2.3 μM inhibiting the growth of Kasumi-1 cells. | ||
| M21707 | Recombinant Mouse HSP70 Protein (HEK293, His Tag) | Cytokines and Growth Factors |
| HSPA1A; heat shock 70kDa protein 1A | ||
| HSPA1A is a member of the Hsp70 protein family. The 70 kilodalton heat shock proteins (Hsp70s) are a family of ubiquitously expressed heat shock proteins. The Hsp70 family stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. | ||
| M4618 | Eupalinolide A | HSP |
| Eupalinolide A, isolated from Eupatorium lindleyanum, induces the expression of HSP70 via the activation of HSF1 by inhibiting the interaction between HSF1 and HSP90. | ||
| M28403 | HSP70-IN-4 | HSP |
| HSP70-IN-4 (Compound YM-01) is an Hsp70 inhibitor with an IC50 of 3.2 μM. HSP70-IN-4 is not BBB permeable. | ||
| M28715 | JG-231 | HSP |
| JG-231 is an analogue of JG-98 with anticancer effects. JG-231 inhibits the interaction of Hsp70-BAG3. JG-231 inhibits MDA-MB-231 heterograft tumor models of triple negative breast cancer (TNBC). | ||
| M29338 | SPL-707 | Gamma-secretase/Beta-secretase |
| SPL-707 is an orally active, selective signal peptide peptidase-like 2a (SPPL2a) inhibitor with an IC50 of 77 nM for hSPPL2a. SPL-707 inhibits γ-secretase (IC50=6.1 μM) and SPP (IC50=3.7 μM). SPL-707 has the potential for autoimmune diseases research by targeting B cells and dendritic cells. | ||
| M30058 | YM-1 | HSP |
| YM-1 is a stable and soluble MKT-077 analog and an orally active Hsp70 inhibitor. YM-1 induces cell death of HeLa cells and up-regulates the level of p53 and p21 proteins. | ||
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