HS38 - Search Results | AbMole BioScience

About 4 results found for searched term "HS38" (0.147 seconds)

Cat.No.	Name	Target
M49488	HS38	DAPK
	HS38 is a potent, selective, ATP-competitive inhibitor of DAPK1 and ZIPK (DAPK3) with Kd values of 300 nM and 280 nM, respectively.In addition, HS38 is an inhibitor of PIM3 with an IC50 value of 200 nM.HS38 has been used in the study of smooth muscle-related diseases.
M22527	Cinchonidine	Alkaloids
	α-Quinidine
	Cinchonidine (α-Quinidine) is a cinchona alkaloid found in Cinchona officinalis and Gongronema latifolium. Cinchonidine (α-Quinidine) is a weak inhibitor of serotonin transporter (SERT) with Ki values of 330, 4.2, 36, 196, 15 μM for dSERT, hSERT, hSERT I172M, hSERT S438T, hSERT Y95F, respectively.
M30757	ABT-384	Hydroxysteroid dehydrogenase
	ABT-384 is a potent, selective 11-β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor. ABT-384 exhibits high affinity (Ki 0.1-2.7 nM) against rodent, monkey, and human 11β-HSD1. ABT-384 blocks regeneration of active cortisol. ABT-384 can be used for the research of Alzheimer’s disease (AD).
M58134	Diphenyl-1-pyrenylphosphine	Fluorescent Dye
	DPPP; 1-(Diphenylphosphino)pyrene
	Diphenyl-1-pyrenylphosphine (DPPP) is a probe that reacts with hydroperoxides to yield the fluorescent molecule diphenyl-1-pyrenylphosphine oxide (DPPP-O). DPPP has also been used as a fluorescent probe for the detection of low density lipoprotein and cellular oxidation. Fluorescence of DPPP-O can be monitored using excitation and emission wavelengths of 351 nm and 380 nm, respectively.