About 3 results found for searched term "HIF-2α-IN-1" (0.152 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M14449 | HIF-2α-IN-1 | HIF |
| HIF-2α-IN-1 is a HIF-2α inhibitor has an IC50 of less than 500 nM in HIF-2α scintillation proximity assay. | ||
| M11025 | M1001 | HIF |
| M1001 is a weaker HIF-2α agonist that binds directly to the HIF-2α PAS-B domain.Kd The value is 667 nM. The M1001 enhances stability between HIF-2α-ARNT complexes. | ||
| M27620 | AKB-6899 | HIF |
| AKB-6899, a prolyl hydroxylase domain 3 (PHD3) inhibitor, is a selective HIF-2α stabilizer. AKB-6899 also increases soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated macrophages, and has antitumor and antiangiogenic effects. | ||
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