About 4 results found for searched term "HIF-2α-IN-1" (0.132 seconds)
Cat.No. | Name | Target |
---|---|---|
M14449 | HIF-2α-IN-1 | HIF |
HIF-2α-IN-1 is a HIF-2α inhibitor has an IC50 of less than 500 nM in HIF-2α scintillation proximity assay. | ||
M11025 | M1001 | HIF |
M1001 is a weaker HIF-2α agonist that binds directly to the HIF-2α PAS-B domain.Kd The value is 667 nM. The M1001 enhances stability between HIF-2α-ARNT complexes. | ||
M27620 | AKB-6899 | HIF |
AKB-6899, a prolyl hydroxylase domain 3 (PHD3) inhibitor, is a selective HIF-2α stabilizer. AKB-6899 also increases soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated macrophages, and has antitumor and antiangiogenic effects. | ||
M56699 | HIF-2α-IN-2 | HIF |
HIF-2α-IN-2 is a hypoxia-inducible factors (HIF-2α) inhibitor, has an IC50 of 16 nM in scintillation proximity assay (SPA). |
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