About 5 results found for searched term "HER2-IN-13" (0.123 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M42090 | HER2-IN-13 | EGFR/HER2 |
| HER2-IN-13 is an HER2 inhibitor with an IC50 of 8 nM. | ||
| M10709 | TAS0728 | EGFR/HER2 |
| TAS0728 is an effective, selective, oral, irreversible, covalently bound HER2 inhibitor covalently bound to the C805 site of HER2, inhibiting its activity.IC50 The value is 13 nM. TAS0728 to BMX, HER4, BLK, EGFR, JAK3, SLK, LOK and HUMAN HER2 IC50 The values are 4.9, 8.5, 31, 65, 33, 25, 86, and 36 nM, respectively. TAS0728 simultaneously inhibits phosphorylation of HER2, HER3 and its downstream effector proteins. Has antitumor activity. | ||
| M14140 | Pyrotinib dimaleate | EGFR/HER2 |
| SHR-1258 dimaleate | ||
| Pyrotinib dimaleate (SHR-1258 dimaleate) is a potent and selective EGFR/HER2 dual inhibitor with IC50s of 13 and 38 nM, respectively. | ||
| M15071 | Recombinant Mouse FGF-9 (E.coli,N-6His) | Cytokines and Growth Factors |
| Fibroblast growth factor 9;FGF-9;Glia-activating factor | ||
| Recombinant mouse fibroblast growth factor 9 was produced by the escherichia coli expression system, and the target gene encoding MET1-SER208 was expressed as 6His at the C-terminal. Accession # : P54130. | ||
| M24993 | Cinrebafusp alfa | EGFR/HER2 |
| PRS 343 | ||
| Cinrebafusp alfa (PRS 343) is a high affinity CD137/HER2 bispecfic anticalin-based drug. Cinrebafusp alfa binds to recombinant human HER2 (Kd=0.3 nM) and human monomeric CD137 (4-1BB; Kd=5 nM). Cinrebafusp alfa facilitates T-cell costimulation by tumor-localized, HER2-dependent 4-1BB clustering and activation, further enhancing T-cell receptor-mediated activity and leading to tumor destruction. Cinrebafusp alfa has the potential for HER2+ solid tumors research. | ||
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