About 4 results found for searched term "HDAC-IN-7" (0.31 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M10534 | HDAC-IN-7 | HDAC |
| Chidamide impurity | ||
| HDAC-IN-7 (Chidamide impurity) is an impurity of Chidamide. Tucidinostat (HBI-8000; Chidamide; CS-055) is a benzamide type inhibitor of histone deacetylase (HDAC) isoenzymes 1, 2, 3 and 10 with IC50 values of 95, 160, 67, 78 nM for HDAC1, 2, 3, 10 respectively. | ||
| M28474 | HDAC3-IN-T247 | HDAC |
| HDAC3-IN-T247 is a potent and selective HDAC3 (histone deacetylase 3) inhibitor, with an IC50 of 0.24 µM. HDAC3-IN-T247 induces a selective increase of NF-κB acetylation in HCT116 cells. HDAC3-IN-T247 shows anticancer and antiviral activity. HDAC3-IN-T247 inhibits growth of cancer cells, and activates HIV gene expression in latent HIV-infected cells. | ||
| M41481 | HDAC-IN-57 | HDAC |
| HDAC-IN-57 is an orally active inhibitor of histone deacetylases (HDAC), with IC50s of 2.07 nM, 4.71 nM, 2.4 nM and 107 nM for HDAC1, HDAC2, HDAC6, HDAC8, respectively. | ||
| M41482 | HDAC6-IN-17 | HDAC |
| HDAC6-IN-17 is a potent HDAC6 inhibitor with IC50 values of 150 nM, 1400 nM, and 2300 nM for HDAC6, HDAC8, and HDAC4, respectively. | ||
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