About 19 results found for searched term "Glutathione S-transferase" (0.13 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M21326 | Recombinant Schistosoma Japonicum GST (E. coli) | Cytokines and Growth Factors |
| Glutathione S-transferase class-mu 26 kDa isozyme; GST 26 | ||
| Glutathione S-Transferase (GST), an antioxidant enzyme, is involved in the primary cellular defense mechanism against reactive oxygen species. Glutathione S-transferases (GSTs), previously known as ligandins, comprise a family of eukaryotic and prokaryotic phase II metabolic isozymes best known for their ability to catalyze the conjugation of the reduced form of glutathione (GSH) to xenobiotic substrates for the purpose of detoxification. | ||
| M40919 | Recombinant Human GSTM2 Protein (E. coli, His Tag) | Cytokines and Growth Factors |
| Glutathione S-transferase Mu 2; GST class-mu 2 | ||
| Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2, and GSTM2, is a cytoplasm protein that belongs to the GST superfamily and Mu family. A DNA sequence encoding the native human GSTM2 (Met 1-Lys 218) was expressed, with a polyhistide tag at the N-terminus. | ||
| M50283 | Glutathione S-transferase | Enzymes & Coenzymes |
| Glutathione S-transferase is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||
| M11352 | Coniferyl ferulate | Others |
| Coniferyl ferulate is a potent glutathione S-transferase (GST) inhibitor that reverses multidrug resistance and down-regulates p-glycoprotein. Coniferyl ferulate strongly inhibited human placental glutathione S-transferase with IC50 of 0.3 μM. | ||
| M2557 | Ezatiostat | Apoptosis |
| TER199, TLK199 | ||
| Ezatiostat (TER199, TLK199) is a glutathione analog inhibitor of glutathione S-transferase (GST) P1-1. Ezatiostat leads to JNK activation by inhibiting GSTP1. Ezatiostat stimulates both lymphocyte production and bone marrow progenitor proliferation. | ||
| M5115 | Fluorescein diacetate | Fluorescent Dye |
| FDA; 3,6-Diacetoxyfluoran; Di-O-acetylfluorescein | ||
| Fluorescein diacetate (FDA), a fluorescent probe used for vital staining, is a fluorescently activated by esterolytic activity of human Pi-class glutathione S-transferase (hGSTP1) selectively among various cytosolic GSTs. | ||
| M5834 | Oltipraz | HIF |
| RP 35972; NSC 347901 | ||
| Oltipraz is a potent Nrf2 activator and a potent inducer of Phase II detoxification enzymes, most notably glutathione-S-transferase (GST). | ||
| M14444 | GSTO1-IN-1 | Others |
| GSTO1-IN-1 is a potent glutathione S-transferase omega 1 (GSTO1) inhibitor with an IC50 of 31 nM. | ||
| M14445 | GSTO-IN-2 | Others |
| GSTO-IN-2 is a glutathione S-transferase inhibitor with IC50s of 3.6, 16.3, and 1.4 μM for GSTA2, GSTM1, and GSTP1-1. | ||
| M16083 | Seneciphylline | Transferase |
| Seneciphylline significantly increases the activities of epoxide hydrase and glutathione-S-transferase but causes reduction of cytochrome P-450 and related monooxygenase activities. | ||
| M19273 | Curzerene | Transferase |
| Curzerene inhibits glutathione S-transferase A1 (GSTA1) mRNA and protein expression. Curzerene induces cell apoptosis. | ||
| M29127 | AZD9898 | Transferase |
| AZD9898 is an orally active leukotriene-C4 synthetase (LTC4S, glutathione S-transferase II) inhibitor, with an IC50 of 0.28 nM. AZD9898 mitigates the GABA binding and hepatic toxicity signal. AZD9898 has the potential to treat asthma. | ||
| M29537 | LAS17 | Transferase |
| LAS17 is a potent and selective tyrosine-directed irreversible inhibitor for glutathione S-Transferase Pi (GSTP1) . LAS17 inhibits GSTP1 activity with an IC50 of 0.5 µM. | ||
| M30612 | NBDHEX | Glutathione Peroxidase |
| NBDHEX is a potent glutathione S-transferase P1-1 (GSTP1-1) inhibitor. NBDHEX induces apoptosis of tumor cells. NBDHEX acts as an anticancer agent by inhibiting GSTs catalytic activity, avoiding inconvenience of the inhibitor extrusion from the cell by specific pumps and disrupting the interaction between the GSTP1-1 and key signaling effectors. NBDHEX can also act as late-phase autophagy inhibitor. | ||
| M39152 | Anonaine | Others |
| Anonaine is an antiparasitic agent. Anonaine also is a glutathione S-transferase (GST) inhibitor. | ||
| M40644 | PreScission Protease | Enzymes & Coenzymes |
| HRV 3C Protease; HRV3C Protease | ||
| PreScission Protease is a recombinantly expressed 3C protease of human rhinovirus type 14 with a GST tag in Escherichia coli that specifically recognizes the octapeptide sequence Leu-Glu-Val-Leu-Phe-Gln-Gly-Pro or the core pentapeptide sequence Leu-Phe-Gln-Gly-Pro at low temperature (4°C) and cleaves between Gln and Gly amino acid residues. Pro and enzymatically cleaves between Gln and Gly amino acid residues, commonly used to remove Glutathione S-transferase (GST), His, or other tags from fusion proteins. | ||
| M42432 | GST-IN-1 | Transferase |
| GST-IN-1 is a glutathione S-transferase (GST) inhibitor with IC50s of 1.55 μM (sjGST) and 2.02 μM (hGSTM2), respectively. | ||
| M52613 | S-(2, 4-Dinitrophenyl)glutathione | Metabolite/Endogenous Metabolite |
| S-(2,4-Dinitrophenyl)glutathione is a substrate for glutathione-S-transferase. | ||
| M54457 | TLK117 | Others |
| TLK117, the active metabolite of TLK199, selective inhibits Glutathione S-transferase P1–1 (GSTP1-1) with a Ki of 0.4 μM for GSTP. | ||
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