About 8 results found for searched term "Glucocerebrosidase" (0.131 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M42351 | Glucocerebrosidase | Metabolite/Endogenous Metabolite |
| Glucocerebrosidase (Glucosylceramidase; GBA) is a lysosomal enzyme that catalyzes the cleavage of β-glucosidic linkage of glucocerebroside (GC) into glucose and ceramide. | ||
| M42409 | Glucocerebrosidase-IN-1 hydrochloride | Glucosidase |
| Glucocerebrosidase-IN-1 hydrochloride is a potent and selective GCase (glucocerebrosidase) inhibitor, with an IC50 of 29.3 μM and a Ki of 18.5 μM. | ||
| M8195 | LTI-291 | Glucosidase |
| Gcase activator 1 | ||
| LTI-291 is an activator of glucocerebrosidase (Gcase). | ||
| M20817 | ML198 | Others |
| ML198 is a novel activator of glucocerebrosidase (GCase) and does not inhibit the enzyme's action, but can facilitate its translocation to the lysosome. | ||
| M21399 | NCGC 607 | Others |
| NCGC607 is a non-inhibitory molecular chaperone of glucocerebrosidase (Gcase). | ||
| M30232 | Glucosylsphingosine | Others |
| Glucopsychosine; Lyso-Gb1 | ||
| Glucosylsphingosine (lyso-Gb1) is a deacylated form of glucosylceramide and is also degraded by the glucocerebrosidase. Glucosylsphingosine is a very promising, reliable and specific biomarker for monitoring Gaucher disease. | ||
| M40762 | BIA 28-6156 | Others |
| BIA 28-6156 is an orally active beta-glucocerebrosidase (GCase) variant activator that improves lysosomal function through activation of GCase and can be used in studies related to Parkinson's disease (PD) with GBA gene mutations. | ||
| M56694 | NCGC00092410 | Glucosidase |
| NCGC00092410 is a potent, selective, and nonsugar glucocerebrosidase (GC) inhibitor, with an IC50 of 31 nM. | ||
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