About 2 results found for searched term "Glembatumumab" (0.545 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M24535 | Glembatumumab | Others |
| Glembatumumab is a fully human IgG2 monoclonal antibody directed against the extracellular structural domain of GPNMB expressed in human breast cancer and melanoma. Glembatumumab can be coupled to the microtubule inhibitor monomethyl auristatin E to form glembatumumab vedotin. Glembatumumab vedotin is an antibody-drug coupling (ADC) with antitumor activity. | ||
| M58984 | Glembatumumab vedotin | Antibody-Drug Conjugates (ADCs) |
| CDX-011; CR011-vcMMAE | ||
| Glembatumumab vedotin (CDX-011) is an antibody-drug conjugate (ADC) comprising a fully human IgG2 monoclonal antibody (CR011) directed against glycoprotein NMB (GPNMB) and conjugated to the potent tubulinbinding cytotoxic agent MMAE via a protease-sensitive vc linker. Glembatumumab vedotin has potent anticancer effects. | ||
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