About 3 results found for searched term "Geldanamycin" (0.12 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3561 | Geldanamycin | HSP |
| NSC 122750; GDM | ||
| Geldanamycin is a natural existing HSP90 inhibitor with Kd of 1.2 μM, specifically disrupts glucocorticoid receptor (GR)/HSP association. | ||
| M8417 | Geldanamycin-Biotin | Others |
| Geldanamycin-Biotin is a benzoquinone ansamycin antitumor antibiotic. | ||
| M20676 | Pimitespib | HSP |
| TAS-116 | ||
| TAS-116 is a novel, small-molecule HSP90 inhibitor which inhibits geldanamycin-FITC binding to HSP90 proteins with Ki values of 34.7 nmol/L, 21.3 nmol/L, >50,000 nmol/L, and >50,000 nmol/L for HSP90α, HSP90β, GRP94, and TRAP1, respectively. Furthermore, TAS-116 does not inhibit other ATPases such as HSP70 (IC50 >200 μmol/L). | ||
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