About 1 result found for searched term "GSK5182" (0.254 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M20777 | GSK5182 | Estrogen Receptor |
| GSK5182 is a 4-Hydroxytamoxifen analog and a highly potent, selective, orally active estrogen-related receptor gamma (ERRγ) inverse agonist with an IC50 value of 79 nM.GSK5182 does not interact with other nuclear receptors, including ERRα and ERα. In addition, GSK5182 inhibits proinflammatory cytokine-induced catabolic factors and increases ROS production in liver cancer cells. cytokine-induced catabolic factors and increased ROS production in hepatocellular carcinoma cells. | ||
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