About 3 results found for searched term "GSK-843" (0.108 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1855 | Dabrafenib Mesylate | Raf |
| GSK-2118436B | ||
| Dabrafenib (GSK2118436) is a selective, orally bioavailable inhibitor of Mutant B-raf (BRAF) protein kinase with potential antineoplastic activity. | ||
| M1988 | Dabrafenib | Raf |
| GSK2118436 | ||
| Dabrafenib (free base) (GSK2118436A) is a V600 mutant BRAF-specific inhibitor. | ||
| M13358 | GSK-843 | Necroptosis |
| GSK'843 | ||
| GSK-843 is a potent receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds RIP3 kinase domain with an IC50 of 8.6 nM, and inhibits kinase activity with an IC50 of 6.5 nM. | ||
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