About 6 results found for searched term "GSK-3β inhibitor 8" (0.148 seconds)
Cat.No. | Name | Target |
---|---|---|
M49761 | GSK-3β inhibitor 8 | GSK-3 |
GSK-3β inhibitor 8, a thiophenacil derivative, is an effective and selective inhibitor of GSK-3β (IC50=64 nM). | ||
M2354 | 1-Azakenpaullone | GSK-3 |
1-Azakenpaullone is a potent and selective GSK-3β inhibitor with IC50 of 18 nM, >100-fold selectivity over CDK1/cyclin B and CDK5/p25. | ||
M2405 | AR-A014418 | GSK-3 |
GSK-3β Inhibitor VIII | ||
AR-A014418 is an ATP-competitive, and selective GSK3β inhibitor with IC50 and Ki of 104 nM and 38 nM, without significant inhibition on 26 other kinases tested. | ||
M10108 | Indirubin-3'-monoxime | GSK-3 |
I3MO | ||
Indirubin-3'-monoxime is a potent GSK-3β inhibitor with IC50 of 22 nM, and inhibits Cdk5/p35, Cdk1/cyclin-B and Cdk2/cyclin-E with IC50s of 100, 180, 250 nM. | ||
M29819 | ZLWH-23 | AChR/AChE |
ZLWH-23 is a selective AChE inhibitor (IC50=0.27 μM) with GSK-3β inhibitory property (IC50=6.78 μM). ZLWH-23 possesses selectivity for AChE over BChE (IC50=20.82 μM) and for GSK-3β over multi-kinases. ZLWH-23 has the potential for the research of Alzheimer's disease. | ||
M49734 | AChE/GSK-3β-IN-1 | AChR/AChE |
AChE/GSK-3β-IN-1 is a potent, dual AChE/GSK-3β inhibitor with IC50 values of 1.2, 149.8 and 22.4 nM for hAChE , hBChE and hGSK-3β, respectively. |
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