About 2 results found for searched term "GLPG2737" (0.133 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M54863 | GLPG2737 | CFTR |
| GLPG-2737 | ||
| GLPG2737 is a novel potent Type 2 corrector of CFTR. GLPG2737 showed high permeability both in MDCKII-MDRI and Caco-2 cells, with low efflux allowing an elevated absorbed fraction FaxFg and a dose proportional increase in exposure in rat from a dose of 5 to 300 mg/kg, despite a low aqueous thermodynamic solubility. | ||
| M56462 | GLPG2737 | CFTR |
| GLPG2737 is a potent CFTR type 2 corrector, and GLPG2737 can be used in combination with a type 1 co-corrector in the study of cystic fibrosis. | ||
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