About 2 results found for searched term "Flavopiridol" (0.122 seconds)
Cat.No. | Name | Target |
---|---|---|
M1710 | Flavopiridol | CDK |
HMR-1275; Alvocidib; L86-8275 | ||
Flavopiridol (Alvocidib) is a competitive broad-spectrum CDK inhibitor with IC50 of 30,170,100 nM against CDK1, CDK2 and CDK4, respectively. | ||
M3483 | Flavopiridol hydrochloride | CDK |
NSC 649890 HCl; Alvocidib hydrochloride; L86 8275 HCl; HMR-1275 HCl | ||
Flavopiridol competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM. It is 7.5-fold more selective for CDK1/2/4/6 than CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. |
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