About 2 results found for searched term "FTI 276 TFA" (0.131 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M22365 | FTI 276 TFA | Others |
| FTI 276 TFA | ||
| M31040 | GGTI-286 TFA | Ras |
| GGTI-286 TFA, a potent and cell-permeable GGTase I inhibitor, is 25-fold more potent (IC50=2 μM) than the corresponding methyl ester of FTI-276. GGTI-286 TFA selectively inhibits geranylgeranylation of Rap1A over farnesylation of H-Ras in NIH3T3 cells (IC50s=2 and >30 μM, respectively). GGTI-286 TFA also potently inhibits oncogenic K-Ras4B stimulation with an IC50 of 1 μM. | ||
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