About 4 results found for searched term "FR054" (0.129 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M27680 | (6R)-FR054 | Apoptosis |
| (6R)-FR054 is a less active isomer of FR054. | ||
| M54562 | FR054 | Others |
| FR054 is a hexosamine biosynthesis pathway enzyme PGM3 inhibitor with anticancer activity and can be used in studies related to breast cancer. | ||
| M5881 | Piperine | P-glycoprotein |
| Bioperine; 1-Piperoylpiperidine | ||
| Piperine, a natural alkaloid isolated from Piper nigrum L, inhibits P-glycoprotein and CYP3A4 activities with an IC50 value of 61.94±0.054 μg/mL in HeLa cell. | ||
| M45311 | EGFR-IN-57 | EGFR/HER2 |
| EGFR-IN-57 is a potent, orally active EGFR-TK inhibitor with an IC50 value of 0.054 µM. EGFR-IN-57 also inhibits VEGFR-2, CK2α, topoisomerase IIβ, and tubulin polymerization with an IC50 value of 0.087, 0.171, 0.13, and 3.61 µM, respectively. In addition, EGFR-IN-57 induced G2/M and pre-G1 cycle arrest and apoptosis in cancer cells. | ||
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