About 4 results found for searched term "FLT3-IN-20" (0.129 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M43511 | FLT3-IN-20 | FLT3 |
| FLT3-IN-20 is a potent FLT3 inhibitor with IC50 values of 1 and 4 nM for FLT3-D835Y and FLT3-ITD, respectively. | ||
| M5026 | UNC-2025 | FLT3 |
| UNC2025 is a potent, ATP-competitive and highly orally active Mer/Flt3 inhibitor with IC50 values of 0.74 nM and 0.8 nM, respectively. UNC2025 is >45-fold selectivity for MERTK relative to Axl (IC50= 122 nM; Ki = 13.3 nM). UNC2025 exhibits an excellent PK properties. | ||
| M14901 | Tandutinib hydrochloride | FLT3 |
| MLN518 hydrochloride; CT53518 hydrochloride | ||
| Tandutinib hydrochloride (MLN518 hydrochloride) is a potent and selective inhibitor of the FLT3 with an IC50 of 0.22 μM, and also inhibits c-Kit and PDGFR with IC50s of 0.17 μM and 0.20 μM, respectively. | ||
| M28236 | OTS447 | FLT3 |
| OTS447 is a potent FLT3 inhibitor with an IC50 of 21 nM (WO2012016082A1, compound 335). | ||
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