About 3 results found for searched term "FLT3-IN-19" (0.128 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M43515 | FLT3-IN-19 | FLT3 |
| FLT3-IN-19 is a potent and selective FLT3 inhibitor with IC50 of 0.213 nM. | ||
| M29644 | BPR1K871 | FLT3 |
| DBPR114 | ||
| BPR1K871 is a potent and selective dual FLT3/AURKA inhibitor with IC50s of 19 nM and 22 nM for FLT3 and AURKA, respectively, acts as a preclinical development candidate for anti-cancer therapy. | ||
| M30350 | E6201 | MEK |
| ER-806201 | ||
| E6201 (ER-806201) is an ATP-competitive dual kinase inhibitor of MEK1 and FLT3. E6201 inhibits MEK1- induced ERK2 phosphorylation with an IC50 value of 5.2 nM, MKK4-induced JNK phosphorylation with an IC50 value of 91 nM, and MKK6-induced p38 MAPK phosphorylation with an IC50 value of 19 nM. Anti-tumor and anti-psoriasis efficacy. | ||
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