About 1 result found for searched term "FGTI-2734 mesylate " (0.121 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29771 | FGTI-2734 mesylate | Farnesyl Transferase |
| FGTI-2734 mesylate is a RAS C-terminal mimetic dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT) inhibitor with IC50s of 250 nM and 520 nM for FT and GGT, respectively. FGTI-2734 mesylate can prevent membrane localization of KRAS, hence solving KRAS resistance problem and thwarting mutant KRAS patient-derived pancreatic tumors. | ||
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