About 1 result found for searched term "FG 7142" (1.937 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M30609 | FG 7142 | GABA Receptor |
| ZK 39106; LSU-65 | ||
| FG 7142 (ZK 39106; LSU-65), a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor (Ki=91 nM). FG 7142 (ZK 39106; LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 (ZK 39106; LSU-65) can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex. | ||
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