About 3 results found for searched term "FAK-IN-9" (0.216 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M43495 | FAK-IN-9 | FAK |
| FAK-IN-9 is a potent and orally active FAK inhibitor with an IC50 of 27.44 nM. | ||
| M5347 | Y15 | FAK |
| FAK inhibitor Y15; FAK Inhibitor 14 | ||
| Y15 is a novel small molecule FAK phosphorylation inhibitor; specifically block phosphorylation of Y397-FAK and total phosphorylation of FAK. | ||
| M28276 | YH-306 | FAK |
| YH-306 is an antitumor agent. YH-306 suppresses colorectal tumour growth and metastasis via FAK pathway. YH-306 significantly inhibits the migration and invasion of colorectal cancer cells. YH-306 potently suppresses uninhibited proliferation and induces cell apoptosis. YH-306 suppresses the activation of FAK, c-Src, paxillin, and PI3K, Rac1 and the expression of MMP2 and MMP9. YH-306 also inhibita actin-related protein (Arp2/3) complex-mediated actin polymerization. | ||
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