About 1 result found for searched term "Endoxifen (Z-isomer)" (0.124 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M27811 | Endoxifen (Z-isomer) | Estrogen Receptor |
| Endoxifen Z-isomer is the most important Tamoxifen metabolite responsible for eliciting the anti-estrogenic effects of this drug in breast cancer cells expressing estrogen receptor-alpha (ERα). Endoxifen inhibits hERG tail currents at 50 mV in a concentration-dependent manner with IC50 values of 1.6 μM. | ||
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