EZH2-IN-15 - Search Results | AbMole BioScience

About 5 results found for searched term "EZH2-IN-15" (0.136 seconds)

Cat.No.	Name	Target
M41699	EZH2-IN-15	Histone Methyltransferase
	EZH2-IN-15 (SHR2554) is a EZH2 inhibitor.
M2676	EPZ005687	EZH2
	EPZ005687 is a potent, selective EZH2 inhibitor,Ki The value is 24 nM, which is 50 times more selective than EZH1 and 500 times more selective than 15 other methyltransferases.
M11242	EI1	Histone Methyltransferase
	KB-145943
	EI1 (KB-145943) is a novel and effective EZH2 inhibitor, capable of acting on EZH2 (WT) and EZH2 (Y641F) with IC50 values of 15 nM and 13 nM, respectively.
M13846	EPZ011989 trifluoroacetate	Histone Methyltransferase
	EPZ-011989 trifluoroacetate
	EPZ011989 trifluoroacetate is a potent, selective orally bioavailable EZH2 inhibitor with Ki < 3 nM for EZH2 wt and EZH2 Y646; 15-fold selectivity over EZH1 and >3000-fold selectivity over other HMTase.
M28933	ZLD1039	Histone Methyltransferase
	ZLD1039 is a potent, highly selective, and orally bioavailable EZH2 inhibitor. ZLD1039 shows potent and concentration-dependent inhibition of PRC2 enzymatic activity against EZH2 wild-type as well as Y641F, and A677G mutant enzymes with IC50 values of 5.6, 15, and 4.0 nM, respectively. ZLD1039 inhibits breast tumor growth and metastasis.