About 2 results found for searched term "EX229" (0.323 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M20630 | EX229 | AMPK |
| compound 991 | ||
| EX229 (compound 991) is a potent AMPK activator that is 5-10-fold more potent than A769662 in activating AMPK. EX229 has Kd values of 0.06 μM, 0.06 μM and 0.51 μM for α1β1γ1, α2β1γ1, and α1β2γ1, respectively. | ||
| M58160 | 5-(N,N-Hexamethylene)-amiloride | Sodium Channel |
| Hexamethylene amiloride; HMA | ||
| 5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) is a potent Na+/H+ exchanger inhibitor, which decreases the intracellular pH (pHi) and induces apoptosis in leukemic cells. 5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) is also an inhibitor of the HIV-1 Vpu virus ion channel and inhibits mouse hepatitis virus (MHV) replication and human coronavirus 229E (HCoV229E) replication in cultured L929 cells with EC50s of 3.91 μM and 1.34 μM, respectively. | ||
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