About 4 results found for searched term "EGFR-IN-83" (0.136 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M42092 | EGFR-IN-83 | EGFR/HER2 |
| EGFR-IN-83 is an EGFR inhibitor (IC50: 2.53 nM). | ||
| M24812 | Losatuxizumab | EGFR/HER2 |
| ABT-806 | ||
| Losatuxizumab (ABT-806) is an anti-EGFR monoclonal antibody. Losatuxizumab binds to EGFR with EC50s of 0.96 nM for EGFR wild-type, 0.09 nM for EGFRC271A,C283A, 0.12 nM for EGFRvIII, 0.66 nM for EGFR1-501. Losatuxizumab can be used for research of EGFR-expressing cancers. | ||
| M56422 | ZN-A-1041 | EGFR/HER2 |
| ZN-A-1041 inhibits HER2 in BT474 cell and wt-EGFR in H838 cells, with IC50s of 9.5 nM and 12 μM respectively. | ||
| M56420 | JBJ-09-063 | EGFR/HER2 |
| JBJ-09-063 is a mutant-selective allosteric EGFR inhibitor with IC50s of 0.147 nM, 0.063 nM, 0.083 nM and 0.396 nM for EGFR L858R, EGFR L858R/T790M, EGFR L858R/T790M/C797S and EGFRLT/L747S. | ||
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