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 About 3 results found for searched term "EDO-S101" (0.148 seconds)

Cat.No.  Name Target
M3741 Monomethyl auristatin E Microtubule
MMAE, Vedotin; SGD-1010
Monomethyl auristatin E (MMAE; Vedotin) is an antimitotic agent which inhibits cell division by blocking the polymerisation of tubulin.*The compound is unstable in solutions, freshly prepared is recommended
M6070 EDO-S101 HDAC
Tinostamustine; EDO-S-101; EDO-S 101
EDO-S101 is a pan HDAC inhibitor; inhibits HDAC1, HDAC2 and HDAC3 with IC50 values of 9, 9 and 25 nM, respectively.
M25312 Zilovertamab vedotin Drug-Linker Conjugates for ADC
VLS-101; MK-2140
Zilovertamab vedotin (VLS-101) is a novel antibody-drug conjugate comprising the humanized monoclonal antibody zilovertamab and and the anti-microtubule cytotoxin monomethyl vedotin. Zilovertamab vedotin binding to tumor cell ROR1 results in rapid internalization, trafficking to lysosomes, antibody–drug conjugate cleavage, and monomethyl vedotin release. Zilovertamab vedotin induces apoptosis. Zilovertamab vedotin can be used in research of cancer.



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