About 3 results found for searched term "EDO-S101" (0.146 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3741 | Monomethyl auristatin E | Microtubule |
| MMAE, Vedotin; SGD-1010 | ||
| Monomethyl auristatin E (MMAE; Vedotin) is an antimitotic agent which inhibits cell division by blocking the polymerisation of tubulin.*The compound is unstable in solutions, freshly prepared is recommended | ||
| M6070 | EDO-S101 | HDAC |
| Tinostamustine; EDO-S-101; EDO-S 101 | ||
| EDO-S101 is a pan HDAC inhibitor; inhibits HDAC1, HDAC2 and HDAC3 with IC50 values of 9, 9 and 25 nM, respectively. | ||
| M25312 | Zilovertamab vedotin | Drug-Linker Conjugates for ADC |
| VLS-101; MK-2140 | ||
| Zilovertamab vedotin (VLS-101) is a novel antibody-drug conjugate comprising the humanized monoclonal antibody zilovertamab and and the anti-microtubule cytotoxin monomethyl vedotin. Zilovertamab vedotin binding to tumor cell ROR1 results in rapid internalization, trafficking to lysosomes, antibody–drug conjugate cleavage, and monomethyl vedotin release. Zilovertamab vedotin induces apoptosis. Zilovertamab vedotin can be used in research of cancer. | ||
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