About 30 results found for searched term "EA2" (0.273 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2548 | Cysteamine hydrochloride | Animal Modeling |
| β-MEA Hydrochloride; β-Mercaptoethylamine Hydrochloride; 2-Aminoethanethiol Hydrochloride | ||
| Cysteamine HCl, the hydrochloride form of Cysteamine, is also a transglutaminase 2 (TGM2) inhibitor, which can be used to induce gastrointestinal disorders in a mouse model as well as a duodenal ulcer model. In addition, Cysteamine HCl has the ability to modulate the activity of dopamine neurons in the striatum of awake, freely moving rats by inhibiting the increased dopamine release from amphetamine, and has antioxidant activity. | ||
| M4611 | oleanolic acid-3-O-β-D-glucopyranosyl (1→2)-α-L-arabinopyranoside | Others |
| Oleanolic | ||
| M6182 | 7ACC1 | Monocarboxylate Transporter (MCT) |
| DEAC; Coumarin D 1421; D 1421 | ||
| 7ACC1(DEAC; Coumarin D 1421; D 1421) selectively interfere with lactate fluxes in the lactate-rich tumor microenvironment; inhibits lactate influx but not efflux in tumor cells expressing MCT1 and MCT4 transporters. | ||
| M7030 | NITD008 | Anti-infection |
| 7-Deaza-2'-C-acetylene-adenosine; NITD-008 | ||
| NITD008 is a potent and selective flaviviruse inhibitor which can inhibit Dengue Virus Type 2 (DENV-2) with an EC50 of 0.64 μM. | ||
| M9177 | SirReal2 | Sirtuin |
| SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM. | ||
| M10235 | SLIGRL-NH2 | PAR |
| Protease-Activated Receptor-2 Activating Peptide | ||
| SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is an agonist of Protease-Activated Receptor-2 (PAR-2). | ||
| M10237 | Protease-Activated Receptor-2, amide | PAR |
| SLIGKV-NH2 | ||
| Protease-Activated Receptor-2, amide (SLIGKV-NH2) is a highly potent agonist of PAR2 with IC50 of 10.4 uM. | ||
| M11509 | DTNB | Others |
| Ellman’s Reagent; 5,5′-Dithiobis(2-nitrobenzoic acid) | ||
| DTNB (Ellman's Reagent) is a chemical used for quantifying the amount or concentration of sulfhydryl groups. It is often used to detect free sulfhydryl groups. DTNB is also an allosteric inhibitor of dengue virus protease (NS2B-NS3Pro) and Streptomyces protease. | ||
| M11552 | DREADD agonist 21 | AChR/AChE |
| DREADD Agonist 21 is an effective agonist for human muscarinic acetylcholine M3 receptor (hM3Dq) (EC50=1.7 nM). | ||
| M14593 | Keap1-Nrf2-IN-1 | Keap1-Nrf2 |
| Keap1-Nrf2-IN-1 is a Keap1 (Kelch-like ECH-associated protein 1)-Nrf2 (nuclear factor erythroid 2-related factor 2) protein-protein interaction inhibitor, and with an IC50 of 43 nM for Keap1 protein. | ||
| M16378 | Deacetylpseudolaric acid C2 | Diterpenoids |
| Deacetylpseudolaric acid C2 | ||
| M17664 | 2α,3α,24-Trihydroxyolean-12-en-28-oic acid | Triterpenoids |
| 2α,3α,24-Trihydroxyolean-12-en-28-oic acid | ||
| M17668 | 3α,22β-Dihydroxyolean-12-en-29-oic acid | Triterpenoids |
| 3α,22β-Dihydroxyolean-12-en-29-oic acid | ||
| M17672 | 1-O-Deacetyl-2α-hydroxykhayanolide E | Triterpenoids |
| 1-O-Deacetyl-2α-hydroxykhayanolide E | ||
| M17681 | Olean-12-ene-3β,11α-diol | Triterpenoids |
| Olean-12-ene-3β,11α-diol | ||
| M17689 | Oleana-9(11),12-dien-3β-ol | Triterpenoids |
| Oleana-9(11),12-dien-3β-ol | ||
| M17931 | Tenacigenin B, 3-O-β-Allopyranosyl-(1→4)-β-oleandropyranosyl-11-O-isobutyryl-12-O-acetyl- | Others |
| Tenacigenin B, 3-O-β-Allopyranosyl-（1→4）-β-oleandropyranosyl-11-O-isobutyryl-12-O-acetyl- | ||
| M17957 | EntadamideA2'-O-(6''-O-β-D-glucopyranosyl)-β-D-glucopyranoside | Others |
| EntadamideA2'-O-（6''-O-β-D-glucopyranosyl）-β-D-glucopyranoside | ||
| M18697 | Raddeanoside 20 | Others |
| Raddeanoside 20 | ||
| M18825 | Theasaponin E2 | Others |
| Theasaponin E2 | ||
| M20953 | 2-Aminoethanethiol | Others |
| cysteamine, β-Mercaptoethylamine, 2-Mercaptoethylamine, Decarboxycysteine, Thioethanolamine, Mercaptamine | ||
| 2-Aminoethanethiol (cysteamine) is a radiation-protective agent that oxidizes in air to form cystamine. | ||
| M21301 | Pelacarsen | Others |
| AKCEA-APO(a)-LRx; TQJ230 | ||
| Pelacarsen (AKCEA-APO(a)-LRx) is a liver-specific, antisense oligonucleotide targeting apolipoprotein(a) that reduces lipoprotein(a) by 80% and is well tolerated. | ||
| M21346 | Recombinant Human Cuteaneous T-cell Attracting Chemokine/CCL27 (E.coli ) | Cytokines and Growth Factors |
| AA Sequence：FLLPPSTACC TQLYRKPLSD KLLRKVIQVE LQEADGDCHL QAFVLHLAQR SICIHPQNPS LSQWFEHQER KLHGTLPKLN FGMLRKMG.Accession: Q9Y4X3. | ||
| M24703 | Cergutuzumab amunaleukin | IL Receptor/Related |
| CEA-IL2v; RG 7813; RO 6895882 | ||
| Cergutuzumab amunaleukin (CEA-IL2v) is a monomeric carcinoembryonic antigen (CEA)-targeted IL-2 variant-based immunocytokine. Cergutuzumab amunaleukin has immunostimulating and antineoplastic activities. | ||
| M45057 | Recombinant Human IDO Protein (E.coli, N-6His) | Cytokines and Growth Factors |
| Indoleamine 2,3-dioxygenase | ||
| Indoleamine 2,3-dioxygenase (IDO) is a heme enzyme that initiates the oxidative degradation of the least abundant, essential amino acid, l-tryptophan, along the kynurenine pathway. | ||
| M30492 | (R)-TAPI-2 | Others |
| (R)-TNF Protease Inhibitor 2 | ||
| (R)-TAPI-2 is the isomer of TAPI-2. TAPI-2 (TNF Protease Inhibitor 2) is a broad-spectrum inhibitor of matrix metalloprotease (MMP), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM), with an IC50 of 20 μM for MMP. TAPI-2 blocks the entry of infectious SARS-CoV. | ||
| M39212 | Stipuleanoside R2 | NF-κB |
| Stipuleanoside R2 inhibits NF-κB activation stimulated by TNFα in a dose-dependent manner with IC50 value of 4.1 μM. | ||
| M40152 | 11α,12α-Epoxy-3β,23-dihydroxy-30-norolean-20(29)-en-28 | Others |
| 11α,12α-Epoxy-3β,23-dihydroxy-30-norolean-20(29)-en-28 is a triterpenoid that isolated from Paeonia Lactiflora. | ||
| M40824 | Polyethylenimine, Linear (MW 25000, liquid) | Cell Transfection |
| PEI | ||
| Polyethylenimine Linear (PEI) solution consists of a cationic polymer transfection reagent with a molecular weight of 25,000, which forms a complex with nucleic acids and allows the complex to enter mammalian cells. | ||
| M40825 | Polyethylenimine, Linear (MW 25000) | Cell Transfection |
| Polyethylenimine Linear (PEI) solution consists of a cationic polymer transfection reagent with a molecular weight of 25,000, which forms a complex with nucleic acids and allows the complex to enter mammalian cells. In addition, Polyethylenimine Linear is one of the most commonly used reagents in small to large scale transfection. | ||
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