About 2 results found for searched term "E6446" (0.418 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9289 | E6446 dihydrochloride | TLR |
| E6446 2HCl; E-6446 hydrochloride | ||
| E6446 dihydrochloride is a potent and orally acitve antagonist of TLR7 and TLR9. E6446 dihydrochloride is also a potent SCD1 inhibitor (KD: 4.61 μM), significantly inhibiting adipogenic differentiation and hepatic lipogenesis through SCD1-ATF3 signaling. | ||
| M11308 | E6446 | TLR |
| E-6446 | ||
| E6446 is an inhibitor of Toll-like receptor (TLR) 7 and 9 signaling in a variety of human and mouse cell types and inhibits DNA-TLR9 interactions in vitro. E6446 is also a potent SCD1 inhibitor (KD: 4.61 μM), significantly inhibiting adipogenic differentiation and hepatic lipogenesis through SCD1-ATF3 signaling. | ||
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