About 15 results found for searched term "E3 ligase Ligand 3" (0.153 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9833 | E3 ligase Ligand 3 | Ligand for E3 Ligase |
| Thalidomide-O-COOH; Cereblon ligand 3 | ||
| E3 ligase Ligand 3 (Thalidomide-O-COOH) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein, it connected to the ligand for protein by a linker to form PROTACs. | ||
| M9836 | Pomalidomide-PEG4-C-COOH | E3 Ligase Ligand-Linker Conjugates |
| E3 Ligase Ligand-Linker Conjugates 1 | ||
| Pomalidomide-PEG4-C-COOH (E3 Ligase Ligand-Linker Conjugates 1) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker. | ||
| M14866 | E3 ligase Ligand 8 | Ligand for E3 Ligase |
| E3 ligase Ligand 8 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 8 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins. | ||
| M22448 | Thalidomide-NH-PEG3-propionic acid | PROTAC |
| Thalidomide-NH-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology. | ||
| M54696 | DGY-09-192 | PROTAC |
| DGY-09-192 is a bivalent degrader that couples the pan-FGFR inhibitor BGJ398 to the CRL2VHL E3 ligase-recruiting ligand, which induces degradation of FGFR1/2 and largely avoids degradation of FGFR3/4.DGY-09-192 exhibits a nanomolar DC50 against both wild-type FGFR2 and several FGFR2 fusions. In addition, DGY-09-192 has antiproliferative activity in gastric and cholangiocarcinoma cells. | ||
| M57108 | (S,R,S)-AHPC-C3-NH2 | E3 Ligase Ligand-Linker Conjugates |
| (S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. | ||
| M57107 | (S,R,S)-AHPC-C8-NH2 | E3 Ligase Ligand-Linker Conjugates |
| (S,R,S)-AHPC-C8-NH2 (VH032-C8-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. | ||
| M57106 | (S,R,S)-AHPC-C7-amine | E3 Ligase Ligand-Linker Conjugates |
| (S,R,S)-AHPC-C7-amine (VH032-C7-amine) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for estrogen-related receptor α (ERRα) PROTAC degrader. | ||
| M57105 | VH032-PEG3-acetylene | E3 Ligase Ligand-Linker Conjugates |
| VH032-PEG3-acetylene is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. | ||
| M57104 | (S,R,S)-AHPC-C3-NH2 TFA | E3 Ligase Ligand-Linker Conjugates |
| (S,R,S)-AHPC-C3-NH2 TFA (VH032-C3-NH2 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. | ||
| M57100 | (S,R,S)-AHPC-C3-NH2 hydrochloride | E3 Ligase Ligand-Linker Conjugates |
| (S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. | ||
| M57097 | (S,R,S)-AHPC-C8-NH2 hydrochloride | E3 Ligase Ligand-Linker Conjugates |
| (S,R,S)-AHPC-C8-NH2 (VH032-C8-NH2) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. | ||
| M57090 | (S,R,S)-AHPC-C7-amine hydrochloride | E3 Ligase Ligand-Linker Conjugates |
| (S,R,S)-AHPC-C7-amine (VH032-C7-amine) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for estrogen-related receptor α (ERRα) PROTAC degrader. | ||
| M57089 | (S,R,S)-AHPC-C8-NH2 dihydrochloride | E3 Ligase Ligand-Linker Conjugates |
| (S,R,S)-AHPC-C8-NH2 dihydrochloride (VH032-C8-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. | ||
| M57085 | (S,R,S)-AHPC-phenol-alkylC6-amine dihydrochloride | E3 Ligase Ligand-Linker Conjugates |
| (S,R,S)-AHPC-phenol-alkylC6-amine dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and an alkyl linker used for PROTAC degrader. | ||
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