About 2 results found for searched term "Duocarmycin A " (0.129 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M27896 | Duocarmycin A | Antibiotic |
| Duocarmycin A, which is one of well-known antitumor antibiotics, is a DNA alkylator and efficiently alkylates adenine N3 at the 3′ end of AT-rich sequences in the DNA. Duocarmycin A, as a chemotherapeutic agent, results HLC-2 cells typically apoptotic changes, including chromatin condensation, sub-G1 accumulation in DNA histogram pattern, and decrease in procaspase-3 and 9 levels. | ||
| M55745 | Duocarmycin SA | Antibiotic |
| Duocarmycin SA is an orally active antitumor antibiotic with an IC50 of 10 pM. | ||
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