About 4 results found for searched term "DprE1-IN-8" (0.187 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M41026 | DprE1-IN-8 | Antibiotic |
| DprE1-IN-8 is a potent DprE1 inhibitor with an IC50 value of <0.75 μM. | ||
| M28285 | Macozinone | Antibiotic |
| PBTZ169 | ||
| Macozinone (PBTZ169) is a bactericidal benzothiazinone and a potent DprE1 (decaprenylphosphoryl-β-d-ribose 2′-oxidase) inhibitor. Macozinone inhibits the essential flavoprotein DprE1 by forming a covalent bond with the active-site Cys387 residue. Macozinone has antituberculosis effect. | ||
| M28691 | DprE1-IN-2 | Antibiotic |
| DprE1-IN-2 (compound 18) is a potent DprE1 inhibitor with an IC50 of 28 nM. DprE1-IN-2 has antituberculosis effect. | ||
| M28987 | Quabodepistat | Antibiotic |
| OPC-167832 | ||
| Quabodepistat (OPC-167832) is a potent and orally active dprE1 inhibitor with an IC50 of 0.258 μM. Quabodepistat has antituberculosis activity and can be used for the research of tuberculosis caused by Mycobacterium tuberculosis. | ||
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