About 3 results found for searched term "Dantrolene" (1.409 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5550 | Dantrolene sodium hemiheptahydrate | Calcium Channel |
| Dantrolene sodium salt, Dantrium, Sodium dantrolene | ||
| Dantrolene sodium hemiheptahydrate ia a skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. | ||
| M7778 | Dantrolene sodium salt | Calcium Channel |
| F 440 | ||
| Dantrolene sodium is an orally active, non-competitive glutathione reductase inhibitor with a Ki of 111.6 μM and an IC50 of 52.3 μM. Dantrolene sodium is also a calcium channel protein inhibitor. Dantrolene sodium inhibits the release of Ca2+ from RyR1 and RyR3, which can be beneficial in a variety of pathologies caused by disruptions in calcium homeostasis. | ||
| M30543 | Dantrolene | Others |
| F 368 | ||
| Dantrolene (F368) non-competitively inhibits human erythrocyte glutathione reductase. Ki and IC50 values are 111.6 μM and 52.3 μM, respectively. Dantrolene is a ryanodine receptor antagonist and Ca2+ signaling stabilizer. Dantrolene can be used for the research of muscle spasticity, malignant hyperthermia, Huntington's disease and other neuroleptic malignant syndrome. | ||
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