About 2 results found for searched term "Dalpiciclib" (0.08 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M10930 | Dalpiciclib | CDK |
| SHR-6390 | ||
| Dalpiciclib (SHR-6390) is a highly selective, oral bioavailable inhibitor of CDK4/6 that is used against CDK4 (IC50=12.4 nM) and CDK6 (IC50=9.9 nM) is equivalent. SHR6390 exerts potent antitumor activity in esophageal squamous cell carcinoma by inhibiting phosphorylated Rb protein and inducing G1 cell cycle blocking. | ||
| M45135 | Dalpiciclib hydrochloride | CDK |
| SHR-6390 hydrochloride | ||
| Dalpiciclib hydrochloride is an orally active and highly selective CDK4/6 inhibitor with IC50 values of 12.4 nM and 9.9 nM, respectively.Dalpiciclib hydrochloride showed antitumor activity against breast cancer and esophageal squamous cell carcinoma. | ||
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