About 1 result found for searched term "DRI-C21045" (0.28 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M25496 | DRI-C21045 | TNF Receptor |
| DRI-C21045 is a potent and selective inhibitor of the CD40-CD40L costimulatory protein-protein interaction (PPI) with an IC50 of 0.17 µM. DRI-C21045 shows concentration-dependent inhibition of the activation of NF-κB and B cell proliferation all induced by CD40L with IC50s of 17.1 µM and 4.5 µM, respectively. | ||
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