About 11 results found for searched term "Citrate lyase" (0.149 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M52590 | Citrate lyase | Metabolite/Endogenous Metabolite |
| Citrate lyase is an enzyme that converts citrate to oxaloacetate. | ||
| M3762 | BMS303141 | Others |
| BMS303141 is a potent ATP-citrate lyase (ACL) inhibitor with IC50 value of 0.13 uM. | ||
| M5207 | Bempedoic acid (ETC-1002) | AMPK |
| ESP-55016; Bempedoic acid | ||
| Bempedoic acid (ETC-1002) is a novel, first-in-class, orally available ATP-citrate lyase (ACL) inhibitor, Bempedoic acid (ETC-1002) can activate AMPK. | ||
| M6945 | MEDICA 16 | Others |
| MEDICA 16 is a fFA1 (GPR40) agonist; also inhibits ATP citrate lyase. | ||
| M9587 | NDI-091143 | ATPase |
| NDI-091143 is a novel potent inhibitor of human ATP-citrate lyase with an IC50 of 2.1 nM (ADP-Glo assay), a Ki of 7.0 nM and a Kd of 2.2 nM. NDI-091143 inhibits ACLY catalysis allosterically, by stabilizing large conformational changes in the citrate domain that indirectly block the binding and recognition of citrate. | ||
| M9614 | SB-204990 | Others |
| SB204990 | ||
| SB-204990 is a potent and specific ATP citrate-lyase inhibitor. | ||
| M10864 | Nicodicosapent | Others |
| Nicodicosapent is a fatty acid niacin conjugate that inhibits the activity of sterol regulatory element binding proteins (SREBP) and the activity of proteins that regulate cholesterol metabolism such as PCSK9, HMG-CoA reductase, ATP citrate lyase, and NPC1L1. | ||
| M42290 | Forrestiacids K | Others |
| Forrestiacids K, a terpenoid isolated from Pseudotsuga forrestii, acts as an ATP-citrate lyase (ACL) inhibitor. | ||
| M42291 | Forrestiacids J | Others |
| Forrestiacids J is an ATP-citrate lyase (ACL) inhibitor with an IC50 of 2.6 μM. | ||
| M45243 | Hydroxycitric acid tripotassium hydrate | Others |
| Potassium citrate monohydrate | ||
| Hydroxycitric acid tripotassium hydrate, the main active ingredient of Garcinia Cambogia, competitively inhibits ATP citrate lyase activity. In addition, Hydroxycitric acid tripotassium hydrate inhibits stone formation and HIF, and has antioxidant, anti-inflammatory and antitumor activities. | ||
| M53926 | Cyclo(L-Phe-L-Val) | Antifungal |
| Cyclo(L-Phe-L-Val) is a potent inhibitor of enzymes isocitrate lyase (ICL) (IC50=27 μg/mL). | ||
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