About 30 results found for searched term "Cathepsin G" (0.124 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M52652 | Cathepsin G | Cathepsin |
| Cathepsin G acts as a potent agonist of human platelet activation leading to their aggregation., and can be used for screening of relevant inhibitors. | ||
| M53632 | Cathepsin G(1-5) | Antibiotic |
| Cathepsin G(1-5) is an antimicrobial peptide that can be found in the clostripain-digested cathepsin G mixture. | ||
| M1985 | Odanacatib | Cathepsin |
| MK-0822 | ||
| Odanacatib (MK-0822) is a potent and reversible covalent inhibitor of CathepsinK (CatK) with an IC50 of 0.2 nM/1 nM for human/rabbit cathepsin B, L, and S and is highly selective. | ||
| M2600 | Balicatib | Cathepsin |
| AAE-581 | ||
| Balicatib is a potent and selective inhibitor of cathepsin K; 10-100-fold more potent in cell-based enzyme occupancy assays than against cathepsin B, L, and S. | ||
| M10412 | Val-cit-PAB-OH | ADC Linker |
| Val-cit-PAB-OH is a cathepsin cleavable ADC peptide linker for making MC-Val-Cit-PAB, which is also known as MC-Val-Cit-PAB-OH. | ||
| M13538 | Z-WEHD-FMK | Caspase |
| Z-WEHD-FMK is a potent, cell-permeable and irreversible caspase-1/5 inhibitor. Z-WEHD-FMK also exhibits a robust inhibitory effect on cathepsin B activity (IC50=6 μM). Z-WEHD-FMK can be used to investigate cells for evidence of apoptosis. | ||
| M20820 | Gly-Phe β-naphthylamide | Others |
| Gly-Phe beta-naphthylamide | ||
| Gly-Phe β-naphthylamide (Gly-Phe beta-naphthylamide) is a substrate of cathepsin C that accumulates within the lysosome. Gly-Phe-β-naphthylamide can inhibit the cathepsin-dependent activation of caspase-8. | ||
| M21400 | LHVS | Cathepsin |
| LHVS is a potent, non-selective, irreversible, cell-permeable inhibitor of cysteine protease and cathepsin. lHVS reduces actin ring formation. lHVS inhibits T. gondii invasion with an IC50 of 10 μM. | ||
| M27794 | ALLM | Proteasome |
| Calpain inhibitor II | ||
| ALLM (Calpain inhibitor II) is a potent inhibitor of calpain and cathepsin proteases. ALLM inhibits neuronal cell death and improves chronic neurological function after spinal cord injury (SCI). | ||
| M27825 | KGP94 | Cathepsin |
| KGP94 is a selective inhibitor of cathepsin L with an IC50 of 189 nM. KGP94 inhibits migration and invasion of metastatic carcinoma and shows low cytotoxicity (GI50=26.9 µM) against various human cell lines. | ||
| M28225 | MIV-247 | Cathepsin |
| MIV-247 is a selective cathepsin S inhibitor with Kis of 2.1, 4.2 and 7.5 nM for human, mouse and cynomolgus monkey cathepsin S, respectively. | ||
| M29515 | K777 | Cathepsin |
| K777 is a potent, orally active and irreversible cysteine protease inhibitor. K777 is also a potent CYP3A4 inhibitor with an IC50 of 60 nM and a selective CCR4 antagonist featuring the potent chemotaxis inhibition. K777 irreversibly inhibits Cruzain, the major cysteine protease of Trypansoma cruzi, and cathepsins B and L. K777 is a broad-spectrum antiviral by targeting cathepsin-mediated cell entry. K777 inhibits SARS-CoV and EBOV pseudovirus entry with IC50 values of 0.68 nM and 0.87 nM, respectively. | ||
| M29991 | Relacatib | Cathepsin |
| SB-462795 | ||
| Relacatib (SB-462795) is a novel, potent, and orally active inhibitor of human cathepsins K, L, and V with Ki values of 41 pM, 68 pM, and 53 pM, respectively. Relacatib inhibits endogenous cathepsin K in situ in human osteoclasts and human osteoclast-mediated bone resorption with IC50 values of 45 nM and 70 nM, respectively. Relacatib inhibits bone resorption in vitro in human tissue as well as in cynomolgus monkeys in vivo. | ||
| M30755 | ONO-5334 | Cathepsin |
| ONO-5334 is a potent, selective and orally active cathepsin K inhibitor with Ki values of 0.10 nM, 0.049 nM and 0.85 nM for human, rabbit and rat cathepsin K, respectively. ONO 5334 is an effective antiviral compound against SAR-COV-2 virus activity with an EC50 value of 500 nM. ONO-5334 has the potential for the study of osteoporosis and COVID-19 disease. | ||
| M41002 | AcLys-PABC-VC-Aur0101 intermediate-1 | ADC Linker |
| AcLys-PABC-VC-Aur0101 intermediate-1 is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. | ||
| M42922 | Z-Nle-Lys-Arg-AMC | Others |
| Z-Nle-Lys-Arg-AMC is a fluorogenic peptide substrate that specifically monitors cathepsin B activity over a broad pH range. | ||
| M43194 | Cathepsin B | Enzymes & Coenzymes |
| Cathepsin B is a cysteine protease and is involved in multiple kinds of programmed cell death (including apoptosis, pyroptosis, ferroptosis, necroptosis, and autophagic cell death). | ||
| M43254 | Abz-HPGGPQ-EDDnp | Others |
| Abz-HPGGPQ-EDDnp (Cathepsin K substrate) is a biological active peptide. | ||
| M43261 | Ac-KQKLR-AMC | Others |
| Ac-KQKLR-AMC (Cathepsin S substrate) is a biological active peptide. | ||
| M50354 | Cathepsin L | Enzymes & Coenzymes |
| Cathepsin L is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||
| M50355 | Cathepsin K | Enzymes & Coenzymes |
| Cathepsin K is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||
| M50356 | Cathepsin D | Enzymes & Coenzymes |
| Cathepsin D (CTSD) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||
| M50357 | Cathepsin C | Enzymes & Coenzymes |
| Cathepsin C is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||
| M50869 | Abz-GIVRAK(Dnp) | Others |
| Abz-GIVRAK(Dnp) is the most efficient substrate for cathepsin B and is highly selective for this enzyme among lysosomal cysteine proteases. | ||
| M51719 | MeOSuc-AAPM-PNA | Others |
| Cathepsin G substrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||
| M52661 | Suc-Val-Pro-Phe-pNA | Cathepsin |
| Suc-Val-Pro-Phe-pNA is a substrate for cathepsin G and can be used to detect the activity of this enzyme. | ||
| M52668 | Cathepsin D and E FRET Substrate | Cathepsin |
| Cathepsin D and E FRET Substrate is a fluorogenic substrate for cathepsins D and E and not for B, H or L. | ||
| M52670 | H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH | Cathepsin |
| H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH is a water-soluble polypeptide that can serve as a substrate for cathepsin D, pepsin and pepsinogen. | ||
| M55310 | BI 1291583 | Dipeptidyl Peptidase |
| BI1291583 | ||
| BI 1291583 is a novel selective inhibitor of cathepsin C (CatC; DPP1). BI 1291583 bound human CatC (DPP1) in a covalent, reversible manner, selectively and fully inhibiting CatC enzymatic activity. | ||
| M55722 | Phe-Lys(Trt)-PAB | ADC Linker |
| Phe-Lys(Trt)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs). | ||
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