About 4 results found for searched term "CX546" (0.18 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2293 | CX-5461 | DNA/RNA Synthesis |
| Pidnarulex | ||
| CX-5461 (Pidnarulex) selectively inhibits Pol I-driven transcription of rRNA with IC50 of 142 nM in HCT-116 cells. | ||
| M7707 | CX546 | GluR |
| CX-546; GR-87 | ||
| CX546 is a selective positive AMPA glutamate receptor modulator. | ||
| M13642 | CX-5461 dihydrochloride | DNA/RNA Synthesis |
| CX-5461 dihydrochloride is a potent and orally bioavailable inhibitor of Pol I-mediated rRNA synthesis, with IC50s of 142 nM in HCT-116, 113 nM in A375, and 54 nM in MIA PaCa-2 cells, and shows little or no effect on Pol II (IC50 ≥25 μM). | ||
| M13945 | SCH 546738 | CXCR |
| SCH 546738 is a potent, orally active and non-competitive CXCR3 antagonist, the affinity constant (Ki) of SCH 546738 binding to human CXCR3 receptor is determined to be 0.4 nM in multiple experiments. | ||
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