About 3 results found for searched term "CU-115" (0.125 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M10810 | CU-115 | TLR |
| CU115 | ||
| CU-115 is a potent TLR8 antagonist (IC50=1.04 µM), and shows selective for TLR8 over TLR7 (IC50=>50 µM). CU-115 decreases TNF-α and IL-1β production activated by R-848 in THP-1 cells. | ||
| M2182 | RG108 | DNA Methyltransferase |
| N-Phthalyl-L-tryptophan | ||
| RG108 is a novel small-molecule inhibitors of DNA methyltransferases with IC50 of 115 nM. | ||
| M21755 | Barasertib | Aurora Kinase |
| AZD1152 | ||
| Barasertib (AZD1152), a precursor of Barasertib-hQPA, is a highly selective Aurora B inhibitor with an IC50 of 0.37 nM in a cell-free assay. Barasertib (AZD1152) induces growth arrest and apoptosis in cancer cells. | ||
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