About 2 results found for searched term "CRN04894" (0.231 seconds)
Cat.No. | Name | Target |
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M54862 | CRN04894 | Adrenergic Receptor |
CRN-04894 | ||
CRN04894 is an orally nonpeptide, potent and selective antagonist for adrenocorticotropic hormone (ACTH) acting at the melanocortin 2 receptor (MC2R). CRN04894 blocks the action of ACTH at MC2R, providing a potential novel treatment for the diseases of ACTH excess such as Cushing’s disease, congenital adrenal hyperplasia, and ectopic ACTH-secreting tumors. | ||
M56262 | CRN04894 | Melanocortin Receptor |
CRN04894 is an orally active MC2R antagonist that demonstrates in vivo efficacy in rat model of adrenocorticotropic hormone (ACTH)-stimulated corticosterone secretion. |
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