About 1 result found for searched term "CDK12-IN-2 " (0.119 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M31196 | CDK12-IN-2 | CDK |
| CDK12-IN-2 is a potent, selective and nanomolar CDK12 inhibitor (IC50=52 nM). CDK12-IN-2 is also a strong CDK13 inhibitor due to CDK13 is the closest homologue of CDK12. CDK12-IN-2 inhibits the phosphorylation of Ser2 in the C-terminal domain of RNA polymerase II. CDK12-IN-2 can be used an excellent chemical probe for functional studies of CDK12. | ||
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