About 2 results found for searched term "CBL0137" (5.886 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9302 | CBL0137 | p53 |
| Curaxin 137; CBL-C137 | ||
| CBL0137 is a metabolically stable curaxin that activates p53 with an EC50 value of 0.37 µM and inhibits NF-κB with an EC50 of 0.47 µM. | ||
| M11512 | CBL0137 hydrochloride | p53 |
| Curaxin-137 hydrochloride; CBL-C137 hydrochloride | ||
| CBL0137 hydrochloride is an inhibitor of FACT, the histone molecule chaperone. FACT promotes the formation of chromatin transcription complexes. CBL0137 hydrochlorideye also activated p53 and inhibited NF-κB, with EC50 values of 0.37 and 0.47 μM, respectively. | ||
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