About 2 results found for searched term "CARM1-IN-3" (0.121 seconds)
Cat.No. | Name | Target |
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M41685 | CARM1-IN-3 | Histone Methyltransferase |
CARM1-IN-3 is a potent and selective co-activator associated arginine methyltransferase (CARM1) inhibitor with IC50 values of 0.07, >25 µM for CARM1 and CARM3, respectively. | ||
M27896 | Duocarmycin A | Antibiotic |
Duocarmycin A, which is one of well-known antitumor antibiotics, is a DNA alkylator and efficiently alkylates adenine N3 at the 3′ end of AT-rich sequences in the DNA. Duocarmycin A, as a chemotherapeutic agent, results HLC-2 cells typically apoptotic changes, including chromatin condensation, sub-G1 accumulation in DNA histogram pattern, and decrease in procaspase-3 and 9 levels. |
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