About 14 results found for searched term "BV6" (0.06 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1865 | Bevirimat | HIV Protease |
| BVM, MPC-4326, PA-457 | ||
| Bevirimat (BVM), also known as PA-457 or MPC-4326, is a novel Human Immunodeficiency Virus type 1 (HIV-1) maturation inhibitor. | ||
| M3638 | BV6 | IAP |
| BV6 is a small molecule Smac analog that antagonizes cIAP1 and XIAP. | ||
| M45060 | ABBV-467 | Bcl-2 |
| ABBV-467 is a type IV selective MCL-1 inhibitor for studies related to multiple myeloma. | ||
| M21125 | ABBV-167 | Bcl-2 |
| BCL-2 inhibitor prodrug (ABBV-167) is a phosphate prodrug of venetoclax with the potential ability to study chronic lymphocytic leukemia (CLL). | ||
| M24821 | Eftozanermin alfa | Apoptosis |
| ABBV-621 | ||
| Eftozanermin alfa (ABBV-621) is a second-generation tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) agonist. Eftozanermin alfa induces apoptosis in tumor cells by activation of death receptors 4/5. Eftozanermin alfa can be used for the research of multiple solid and heme malignancies. | ||
| M24916 | Budigalimab | PD-1/PD-L1 |
| ABBV 181; PR 1648817 | ||
| Budigalimab (ABBV 181; PR 1648817) is a humanized IgG1 monoclonal antibody targeting programmed cell death 1 (PD-1) receptor. Budigalimab is Fc mutated thus to reduce Fc receptor interactions and limit effector function. | ||
| M25015 | Revdofilimab | OX Receptor |
| ABBV-368 | ||
| Revdofilimab (ABBV-368) is a human IgG1 agonist monoclonal antibody against OX40. Among them, OX40 is a member of the TNF receptor superfamily expressed on activated and memory T cell subsets and T regulatory cells. | ||
| M41165 | HBV-IN-36 | Anti-infection |
| HBV-IN-36 is a HBV inhibior (IC50=2 μM), showing anti-HBV activity with EC50 of 0.58 μM. | ||
| M49362 | ABBV-668 | RIPK |
| ABBV-668 is a RIPK1 inhibitor that regulates inflammation by inhibiting RIPK1 and inflammatory cytokine production. It can be used in studies related to immune system diseases. | ||
| M53480 | HBV Seq2 aa:179-186 | Anti-infection |
| HBV Seq2 aa:179-186 serve as effective motifs for CTL response in H-2b system after in vitro restimulation of the primed T cells. | ||
| M53507 | HBV Seq1 aa:63-71 | Anti-infection |
| HBV Seq1 aa:63-71 is the fragment of hepatitis B virus (HBV). | ||
| M53509 | HBV Seq2 aa:208-216 | Anti-infection |
| HBV Seq2 aa:208-216, a HBsAg derived CD8 epitope peptide, is studied as part of Large envelope protein from Hepatitis B virus. | ||
| M54649 | Navocaftor | CFTR |
| GLPG 3067; ABBV-3067 | ||
| Navocaftor is a cystic fibrosis transmembrane regulator (CFTR) modulator. | ||
| M55882 | ABBV-467 | Bcl-2 |
| ABBV-467 is a selective MCL-1 inhibitor (Ki: <0.01 nM). | ||
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