About 1 result found for searched term "BRD9876 " (0.118 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29911 | BRD9876 | Kinesin |
| BRD9876 is the “rigor” inhibitor that locks kinesin-5 (Eg5) in a state with enhanced microtubules (MTs) binding, leading to bundling and stabilization of MTs. BRD9876 interacts with the tyrosine 104 residue that is part of the α4-α6 allosteric binding pocket. BRD9876 specifically targets microtubule-bound Eg5 and selectively inhibits myeloma over CD34 cells. BRD9876 has the potential for multiple myeloma (MM) research. | ||
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