About 1 result found for searched term "BMS-986318" (0.118 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M21185 | BMS-986318 | Farnesoid X Receptor |
| BMS-986318 is a potent non-bile acid FXR agonist with an EC50 of 53 and 350 nM in FXR Gal4 and SRC-1 recruitment assays, respectively. BMS-986318 has suitable ADME properties and is effective in a mouse model of hepatic cholestasis and fibrosis with bile duct ligation.BMS-986318 can be used in nonalcoholic steato BMS-986318 can be used in non-alcoholic steatohepatitis (NASH) studies. | ||
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