About 1 result found for searched term "BMS-984923" (0.467 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M59112 | BMS-984923 | GluR |
| BMS-984923 is a potent mGluR5 silent allosteric modulator (SAM), with exquisite binding affinity (Ki = 0.6 nM), exhibits good oral bioavailability and BBB penetration. BMS-984923 potently inhibits the PrPC-mGluR5 interaction and prevents pathological Aβo signaling without affecting physiological glutamate signaling. | ||
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