About 2 results found for searched term "BMS-1166" (0.158 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M10290 | BMS-1166 | PD-1/PD-L1 |
| BMS-1166 free base; BMS1166 | ||
| BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor, which binds to human PD-L1 and blocks its interaction with PD-1. | ||
| M29255 | BMS-1166 hydrochloride | PD-1/PD-L1 |
| BMS-1166 hydrochloride is a potent PD-1/PD-L1 immune checkpoint inhibitor. BMS-1166 hydrochloride induces dimerization of PD-L1 and blocks its interaction with PD-1, with an IC50 of 1.4 nM. BMS-1166 hydrochloride antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation. | ||
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