About 2 results found for searched term "BMPR2-IN-1" (0.13 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M43580 | BMPR2-IN-1 | TGF-β Receptor |
| BMPR2-IN-1 is a BMPR2 inhibitor with an IC50 of 506 nM and a KD of 83.5 nM. | ||
| M55622 | Recombinant Human BMPRIA/ALK-3/CD292 Protein (HEK293, C-His) | Cytokines and Growth Factors |
| Bone Morphogenetic Protein Receptor type IA; Activin receptor-Like Kinase 3; ACVRLK3 | ||
| BMPR1A/ALK-3/CD292 protein is expressed in the epithelium during branching morphogenesis. It is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta (TGF-β) superfamily. BMPR1A/ALK-3 plays an essential role in the formation of embryonic ventral abdominal wall, and abrogation of BMP signaling activity due to gene mutations in its signaling components could be one of the underlying causes of omphalocele at birth. The type IA BMP receptor, ALK-3 was specifically required at mid-gestation for normal development of the trabeculae, compact myocardium, interventricular septum, and endocardial cushion. | ||
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