About 1 result found for searched term "BDE-47" (0.757 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M55229 | BDE-47 | Apoptosis |
| 2,2',4,4'-tetrabromodiphenyl ether | ||
| BDE-47 is an apoptosis inducer involving ROS mediated mitochondrial pathway and Nrf2 pathway activation. BDE-47 reduced cell viability and disrupted mitochondrial dynamics by inhibiting mitochondrial fusion and fission simultaneously, leading to MMP decreases, ROS overgeneration, ATP depletion, and cellular disintegration in a dose-dependent manner. | ||
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